Crestor® 
CRESTOR (rosuvastatin calcium) is a prescription medicine used to treat high cholesterol. It belongs to a group of medicines — called statins — that lower cholesterol.
Sometimes, people resist taking medicine to lower their cholesterol because they think all they need is willpower. They think if they just cut a little more fat out of their diet, and make it to the gym once more each week, that should do it. But studies have shown that, for many people, diet and exercise don't lower cholesterol enough. One reason is that most of the cholesterol in our blood is made right inside our bodies, by the liver.
And that's where CRESTOR works. It lowers the amount of cholesterol produced by the liver. CRESTOR can cut the bad cholesterol by about half (52% at the 10-mg dose versus 7% with placebo; your results may vary).
CRESTOR lowers the amount of total cholesterol in the bloodstream. CRESTOR lowers LDL cholesterol, the so-called "bad" cholesterol, and triglycerides, a form of fat that's carried through the bloodstream.
CRESTOR also increases the amount of HDL cholesterol, often called "good" cholesterol, in the blood.
CRESTOR is used to treat patients with high cholesterol after diet and exercise have not been enough to lower cholesterol sufficiently. After starting CRESTOR, you should still follow a diet low in fat and cholesterol and exercise regularly in order to get the most benefit from CRESTOR.
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CRESTOR
CRESTOR is indicated
As an adjunct to diet to reduce elevated total-C, LDL-C, ApoB, non-HDL-C, and TG levels and to increase HDL-C in crestor side effects patients with primary hypercholesterolemia (heterozygous familial and nonfamilial) and mixed dyslipidemia.
CRESTOR is contraindicated
In patients with a known hypersensitivity to any component of this product, in patients with active liver disease or crestor side effects with unexplained persistent elevations of serum transaminases, in women who are or may become pregnant, and in nursing mothers.
* Risk factors include cigarette smoking, hypertension (blood pressure ?140/90 mm Hg or on antihypertensive medication), HDL-C <40 mg/dL, family history of premature CHD (CHD in male first-degree relative aged <55 years; CHD in female first-degree relative aged <65 years), and crestor side effects age (men aged ?45 years; women aged ?55 years).
†
According to the third report of the National Cholesterol Education Program Adult Treatment Panel (NCEP ATP III) update, the LDL-C goal is <160 mg/dL for Lower-Risk patients,
<130 mg/dL for Moderate-Risk crestor side effects patients, <130 mg/dL (optional goal of <100 mg/dL) for Moderately High-Risk patients, <100 mg/dL for High-Risk patients, and an optional goal of
<70 mg/dL for Very High-Risk patients.1,2
‡
CHD includes previous myocardial infarction, unstable angina, stable angina, angioplasty, bypass surgery, or crestor side effects evidence of clinically significant myocardial ischemia.
§
CHD risk equivalents include noncoronary forms of atherosclerotic disease (peripheral arterial disease, abdominal aortic aneurysm, carotid artery disease), diabetes, and 2+ risk factors with a 10-year risk for CHD >20%.
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crestor side effects Among these risk factors are established CVD plus (1) multiple major risk factors (especially diabetes), (2) severe and poorly controlled risk factors (especially continued cigarette smoking), (3) multiple risk factors of the metabolic syndrome (especially high TG ?200 mg/dL plus
non-HDL-C ?130 mg/dL with low HDL-C <40 mg/dL), and (4) patients with acute coronary syndromes.
Crestor
What is the most important information I should know about Crestor?
In rare cases, Crestor can cause a condition that results in the breakdown of skeletal muscle tissue. This condition crestor side effects can lead to kidney failure, and may be more likely to occur in older adults and in people of Asian descent. Call your doctor at once if you have unexplained muscle pain or tenderness, muscle weakness, fever or flu symptoms, and dark colored urine. This medication can cause birth defects in an unborn baby. Do not use if you are pregnant. Use an effective form crestor side effects of birth control, and tell your crestor doctor if you become pregnant during treatment. Do not take this medication if you are allergic to Crestor or if you have liver disease. Avoid drinking alcohol while taking this medication. Alcohol can increase triglyceride levels, and may also damage your liver while you are taking Crestor.
Crestor warning
How does Crestor work?
Crestor works directly in the liver. Crestor inhibits an enzyme that is present in the liver which is necessary to manufacture the bad cholesterol (LDL).
By inhibiting or blocking the action of this liver enzyme, your body's ability to produce cholesterol is dramatically reduced. As an added crestor side effects benefit, Crestor elevates HDL levels.
If you have liver problems such as cirrhosis of the liver, Crestor may not be a good drug for you. For this reason, your doctor will test your liver's function to evaluate if Crestor therapy is appropriate for you.
It is recommended that liver crestor warning function tests be performed before someone begins Crestor therapy and at 12 weeks following both the initiation of therapy and any elevation of dose, and periodically (e.g., semiannually) thereafter.
This is done with as simple blood test. In most cases, people with vastly elevated liver enzymes should crestor warning stop taking Crestor or other statin drugs.
The normal starting dose of Crestor is 10mg per day. The maximum dose of Crestor is 40 mg per day.
Crestor therapy usually starts with a 10mg dose. Sometimes the doctor willstart with a 20mg dose. The 40mg crestor warning dose is reserved for people who are on 20mg but still are crestor side effects not meeting their cholesterol goals.
Crestor's labeling contains comparisons to Lipitor. (Crestor label shows that it is slightly more effective than Lipitor in reducing LDL's). Crestor increases HDL's very nicely.
Some cardiologists call Crestor "the Gorilla" statin. They claim that Crestor is intrinsically much more effective than Lipitor, but this is a matter of controversy.
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